Marijuana usage can result in the development of problematic use, often known as a marijuana use disorder, which in extreme situations can take the form of addiction.
Marijuana usage issues are frequently linked to dependence, in which case stopping the substance causes withdrawal symptoms. Frequent marijuana users usually describe mood and sleep disturbances, decreased appetite, cravings, restlessness, and/or a variety of bodily discomforts that peak in the first week after quitting and linger up to two weeks. Marijuana dependence happens when the brain becomes less sensitive to and produces less of its own endocannabinoid neurotransmitters as a result of exposure to high doses of the drug. When a person's marijuana use disorder develops to addiction, then it interferes with many areas of their life.